Clinically Proven Ingredients YU WILL LOVE

Skincare products containing alpha-hydroxy acids, or AHA, (glycolic, lactic, tartaric, and citric acids) have become increasingly popular in recent years.


  • fine lines and wrinkles
  • irregular pigmentation
  • age spots
  • shrink enlarged pores.



Mild irritation and sun sensitivity. To avoid burning, you should apply sunscreen in the morning every day,



To help avoid skin irritation, start with a product with a maximum concentration of 10% to 15% AHA. To allow your skin to get used to it, you should only initially apply the skin care product every other day, gradually working up to the daily application.

At a Glance
  • Also known as acetyl hexapeptide-8 and acetyl hexpeptide-3
  • Synthetically derived
  • Has water-binding abilities and skin-restoring properties
  • Is considered a neurotransmitter-inhibiting peptide


  • anti-aging

So this one is the famous peptide marketed by its manufacturer as the “Botox in a jar”. The basis for this claim is that it targets the same wrinkle-forming mechanism (wrinkles caused by facial muscle movement) as Botox, but it works very differently. In addition, the extent to which it can prevent muscles from contracting (and smooth wrinkles) is very different (otherwise, why would anyone still use Botox?).

Research has shown this peptide can penetrate further into the skin if specific formulary steps are followed, including the emulsion type (a higher water content showed greater penetration). This demonstrates the importance of selecting well-formulated skin care products to add to your routine.

The manufacturer did several studies to prove that Argireline works, and it does (just not as well as Botox). In-vivo (made on real people) tests showed that using 10% Argireline solution around the eyes for 15 days decreased wrinkles depth by 17%, while a 5% Argireline formula applied for 28 days did almost the same with a decrease in wrinkle depth by 16.26%. A Spanish University also researched and found that Argireline increased skin moisturization and decreased the depth and width of wrinkles “significantly.”

This means Acetyl Hexapeptide-8 can smooth wrinkles (but not as well as Botox – sorry if we sound like a broken record). Also, we must agree with TruthInAging, that it’s not a collagen builder or a preventer of structural aging (think vitamin CAHAs , or retinol); it’s just a quick fix. If you are looking for one, this could be your thing.

Undeniable research demonstrates how Azelaic Acid significantly diminishes the appearance of skin blemishes, helps fade post-acne marks + other discolorations, refines skin’s surface, and even reduces skin sensitivity. In short, azelaic acid is an ingredient you need to know about.



  • Mild exfoliating action that helps unclog pores and refine skin’s surface
  • Skin tone evening properties to visibly fade post-acne marks and other discolorations
  • Significant skin-calming factors in reducing sensitivity and bumps
  • Antioxidant power that contributes to healthier-looking skin



Azelaic acid products can be used alongside all skin care products, and there isn’t research showing it’s a problem to use alongside other powerhouse ingredients.


  • Protects the skin barrier with a thin undetectable film (great for sensitive, red skin)
  • Prevents cell damage associated with aging or sun-exposed skin
  • May help repair skin sores, dermatitis, eczema, and burns
  • Fends off harmful bacteria (great for your microbiome) and skin viruses
  • A super skin-plumping humectant – equal to, if not better than, Hyaluronic Acid
  • Deeply penetrates the epidermis, smoothing fine lines and wrinkles


  • Removing dead skin cells
  • Improving the texture and color of sun-damaged skin
  • Penetrating oil-laden hair follicle openings to help with acne.



Salicylic acid can be less irritating than skincare products containing alpha-hydroxy acids, but they provide a similar improvement in skin texture and color.

Blueberry extract is a source of pro-retinol which helps to reduce the appearance of the tell-tale signs of aging: fine lines and wrinkles. Combined with the linoleic content which strengthens the skin’s natural barrier, blueberry extract hydrates and plumps the skin, making it look youthful and radiant



  • Break down wrinkle causing glycation bonds
  • Shield skin from sun damage
  • Collagen production
  • Calm and soothes acne
  • Improve the healing process



Just to be clear, blueberries do not replace a broad-spectrum sunscreen; rather, their benefits complement what sunscreen does to protect skin.

Calendula oil has anti-fungal, anti-inflammatory, and antibacterial properties that might make it useful in healing wounds, and soothing eczema.


  • A 2012 laboratory study found that calendula oil had SPF properties as a cream mixture.
  • Calendula oil might accelerate wound healing. Research from 2013 Trusted Source
  • One study found that calendula extract may be useful in treating and preventing acne vulgaris,
  • There is no definitive proof yet, but some people use calendula oil to treat eczema. One study found it can help relieve pain from dermatitis in people receiving radiation.
  • More research is needed, but Calendula oil’s wound-healing properties might make it a good choice in treating psoriasis.
  • One study found that a cream containing calendula extract may promote skin hydration and firmness, but more research is needed.


  • Improve the health of your skin cells
  • Help create a barrier to prevent moisture from leaving your skin
  • Prevent dryness and irritation by locking moisture into your skin
  • Protect your skin from environmental damage
  • Protect your skin from allergy and infection-causing germs like bacteria and fungi
  • Promote anti-aging by keeping your skin moist and supple

Research has shown that it provides its own benefits to the skin while enhancing the stability of other antioxidants, such as vitamins C and E when paired with them. Of note, ferulic acid plays a significant photoprotective role, which is one of the reasons it’s a welcome addition to sunscreen formulations.



  • Photoprotection
  • Inhibit skin discoloration
  • Even skintone
  • Defend against environmental assault
  • Soothe irritated skin

This natural moisturizing ingredient helps repair dry or cracked skin.



  • Repair dry or cracked skin
  • Reduce blackheads, pimples, and acne
  • Improve oily skin



Because of its ability to lock in moisture, you can benefit from using products with glycerin at the end of the day to keep your skin moisturized overnight.

Gotu Kola has potent antioxidant properties, is a rich source of amino acids, and soothes upset or compromised skin.



  • Improve skin’s moisture content
  • Soothes troubled sensitive or acne-prone skin
  • Promotes a healthy skin barrier
  • Keeps skin smooth and intact

Skin care products containing this substance are often used with vitamin C products to assist in effective penetration. Hyaluronic acid (also known as a glycosaminoglycan) is touted for its ability to “reverse” or stop aging. In news reports, you might have heard hyaluronic acid as the “key to the fountain of youth.” This is because the substance occurs naturally (and quite abundantly) in humans and animals and is found in young skin, other tissues, and joint fluid.

LOOK FOR IT! As a smart ingredient, sodium hyaluronate (the salt for of hyaluronic acid) helps skin maintain water balance, which is critical to its healthy appearance. In addition to its moisture-binding (humectant) properties, sodium hyaluronate is also considered a postbiotic, meaning it can help nourish and maintain skin’s microbiome. Sodium hyaluronate is more easily absorbed by the body (more bio-available).



  • Slow the signs of aging
  • Skin retain moisture
  • Give a plump appearance
  • Fight wrinkles caused by glycation



Hyaluronic acid is a component of your body’s connective tissues, and it’s known to cushion and lubricate these tissues. As you age, however, forces of nature destroy hyaluronic acid. Poor diet and smoking can also affect your body’s level of hyaluronic acid over time.

Grape seed extract mitigates the effects environmental stressors have on the skin.



  • Contains proanthocyanidins, polyphenols, flavonoids, and anthocyanins, all of which are very potent antioxidants
  • Helps keep skin youthful by defending against environmental stressors
  • Has also been shown to have soothing properties
  • Red grapes contain resveratrol, considered a very effective anti-aging antioxidant

Camellia sinensis is better known as green tea. Research has established that topical application of green tea leaves or extracts has many benefits for the skin, including anti-aging properties. The polyphenols in green tea possess potent antioxidant and skin-soothing properties and show significant promise for improving the appearance of sun-damaged skin.

White and green tea have nearly identical antioxidant activity, and both are great antioxidants to look for in skincare products.



  • Soothes skin irritations
  • Potent antioxidant capabilities make it an important anti-aging ingredient
  • Potent free-radical scavenger
  • Improves the appearance of sun-damaged skin
  • Has soothing and photoprotective properties

Kojic acid is also a remedy for treating pigment problems and age spots. Discovered in 1989, kojic acid is derived from a fungus, and studies have shown that it’s effective as a lightning agent, slowing the production of melanin (brown pigment).



  • Pigmentation and age spots



With continued use, kojic acid may make your skin susceptible to sunburn. Counteract this by using a sunscreen every day!

Licorice extract offers skin-soothing properties. In addition, it can effectively improve the look of an uneven skin tone. One of its components, known as glabridin, is a potent antioxidant and skin-soothing ingredient, which is why licorice often shows up in products meant for sensitive, reddened skin.



  • Reduced redness from irritation
  • Soothe inflamed skin
  • Fade dark spots

Niacinamide is a form of vitamin B3 that helps build keratin and keep your skin firm and healthy. It can help retain moisture and stop skin flushing.



  • Retain moisture
  • Reduce redness and inflammation
  • Firmness and elasticity



If you have rosacea, face masks with this ingredient can help reduce redness and swelling.

Omega fatty acids are truly remarkable ingredients for skin. They are the essential building blocks of skin’s surface layers, creating a smoother, more even, younger-looking, and healthier complexion, no matter your age or skin type.



  • Omega-3
  • Omega-6
  • Flax seed (linseed) oil
  • Linoleic acid
  • Passion fruit oil



  • Reinforce and smooth skin’s surface
  • Increase hydration without feeling heavy and help keep skin hydrated
  • Calm signs of external stressors, including redness and sensitivity
  • Eliminate signs of flaky, dehydrated-looking skin
  • Visibly strengthen skin against signs of environmental damage
  • Deliver antioxidants to visibly reduce fine lines and wrinkles



Omegas have a natural affinity for skin and are especially beneficial when combined with other skin-loving ingredients like ceramides, cholesterol, and glycerin. This formulary approach is exactly the path we took with our leave-on Omega+ Complex products, all with the same exclusive blend of omega fatty acids.

Panthenol (sometimes referred to as pro-vitamin B5) is a popular humectant in personal care products due to its ability to attract and hold moisture. When topically applied, it converts to pantothenic acid, a naturally occurring substance within the body.



  • Attract and retain moisture
  • Reduce sensitivity-induced redness
  • Aid in healing and skin barrier repair

There are dozens and dozens of remarkable peptides and more being discovered (or made in a lab) every day. Just like antioxidants, skin-soothing ingredients, and skin-replenishing ingredients, there a dozens of brilliant peptides. When all of these elements are combined in a skincare product to address multiple signs of aging, they can do amazing things!



  • Acetyl Hexapeptide-8 (collagen builder)
  • Acetyl Tetrapeptide-2 (regenerates skin)
  • Acetyl Tetrapeptide-5 (stimulates collagen production)
  • Arginine/lysine polypeptide (preserves collagen and elastin)
  • Caprooyl Tetrapeptide-3 (supports natural production of supportive skin substances)
  • Carnosine (collagen boosting, antiglycation properties)
  • Copper Peptide (counteracts free radicals)
  • Matrixyl 3000 (reduces the visible signs of sensitivity)
  • Palmitoyl Oligopeptide (promotes collagen production)
  • Palmitoyl Pentapeptide-4 (improves fine lines + wrinkles)
  • Palmitoyl Tripeptide-5 (stimulates collagen production)
  • Trifluoroacetyl Tripeptide-2 (improves skin elasticity and firmness)
  • Tripeptide-29 (improves fine lines + wrinkles)



  • Skin barrier
  • Appearance of wrinkles
  • Elasticity
  • Inflammation
  • Skin tone
  • and even repair damaged skin
  • Clear breakouts

Retinol is derived from vitamin A and is found in many over-the-counter “anti-aging” skin care products.

Yudoyu® has become a big fan of Bakuchiol. A natural ingredient that mimics the retinol without the often irritating side effects.



  • Acne and acne scarring
  • Mottled pigmentation
  • Fine lines and wrinkles
  • Skin texture
  • Skin tone and color
  • Skin hydration levels.



Vitamin A has a molecular structure that’s tiny enough to get into the lower layers of your skin, where it boosts collagen and elastin. It is also a protein that can strengthen your skin’s flexibility.

Terminalia chebula is an Ayurvedic plant extract that’s native to South Asia, where it’s known as “The King of Medicine”. Terminalia chebula has in vitro research showing it exerts a protective effect on skin exposed to daylight as well as helping to maintain skin’s supportive elements. This plant is a rich source of phenolic compounds that exhibit antioxidant activity. Examples include gallic and ellagic acids, both potent antioxidants; in fact, comparative studies with antioxidants like quercetin has shown the antioxidant mix in Terminalia chebula has 95% efficacy against different types of free radicals.



Neutralizes free radicals and the signs of aging caused by glycation

With age and sun exposure, collagen synthesis in your skin decreases, leading to wrinkles.



  • L-ascorbic Acid
  • Gooseberry (or Amla) if you have very sensitive skin
  • Tetrahexyldecyl Ascorbate
  • THD
  • Magnesium Ascorbyl Phosphate
  • Ascorbyl Tetraisopalmitate



  • Stimulate collagen synthesis
  • Minimize fine lines, scars, and wrinkles
  • Improve the appearance of sun-damage



Initial use of vitamin C-containing creams can cause stinging or redness, but these side effects generally go away with continued use.

Vitamin E is a naturally occurring component of healthy skin and its second most prevalent antioxidant behind ascorbic acid (vitamin C). It offers significant antioxidant properties to help defend against pollution and other environmental stressors that otherwise weaken the skin, causing unwanted changes.

In skin care formulas, vitamin E also works as a good supporting ingredient. For instance, in vitamin C products, vitamin E will donate a key electron that vitamin C (as ascorbic acid) needs to stabilize itself. Vitamin E also works well with other antioxidants such as rosemary, ferulic acid, and the amino acid taurine.



  • d-alpha-tocopherol acetate
  • dl-alpha tocopherol
  • dl-alpha tocopherol acetate
  • soy oil
  • rice bran oil
  • flax oil



  • Repair skin from the damage of environmental stress
  • Visibly improve hyperpigmentation when used in a 1% concentration



What about using pure vitamin E on scars? Although this is a popular tip, research has shown doing so isn’t effective and, in some cases, can make matters worse.

What is witch hazel?

Witch hazel is an astringent derived from the Hamamelis Virginiana plant.

Is witch hazel good for your skin?

Witch hazel is known for an array of benefits, including its ability to soothe the skin and reduce inflammation and the appearance of pores.

Does witch hazel clear skin?

Witch hazel has antibacterial properties, which may fight the bacteria that can cause inflammation in acne-prone skin without leaving it too dry.